Culture Collections

Human Cell Line Authentication by STR Profiling

The European Collection of Authenticated Cell Cultures (ECACC), a founder member of ICLAC (the International Cell Line Authentication Committee), working with external partners, offer a simple and fast human cell line authentication service.

Short tandem repeat (STR) loci are one of the most informative polymorphic markers in the human genome. STR profiles help ensure the quality and integrity of human cell lines in the scientific community.

 STR Profiling - FTA Cards

 

What you need to do:

  1. request the FTA cards and start to grow your cells to the recommended concentration
  2. spot samples of human cells or DNA onto the FTA card and leave to dry
  3. return FTA cards using the pre-addressed envelope provided; no dry ice required!

 

What we provide:

  • STR analysis at 16 loci including Amylogenin
  • expert interpretation of electropherograms 
  • comparison of results with ECACC and publicly available STR profile databases
  • a confidential report

 

You will receive your results within five working days of sample receipt. Additional technical support is available if required.

 

Samples are £135 each or £125 if five or more are ordered.

A custom STR profiling service is also available for bespoke and routine orders, please contact us for further information

CultureCollections.BusinessE@phe.gov.uk

+44 (0)1980 612947

 

Click here to start processing your order

 

Resources

Interpretation of cell line STR profiles - electropherogram

Interpretation of cell line STR profiles - instrumental artefacts

Interpretation of cell line STR profiles - biological artefacts

 

Related links

ICLAC - Guide to human cell line authentication

International Journal of Cancer - Match criteria for human cell line authentication: Where do we draw the line?

 

Back to top
Copyright © Public Health England.

Please confirm your country of origin from the list below.