The glossary is an alphabetical list of acronyms and terms related to our products.
Centre for Applied Microbiology and Research is a previous name of the organisation based at Porton Down, Salisbury, UK. It was formerly MRE and subsequently part of the Health Protection Agency (HPA) which was subsumed into Public Health England in April 2013
Collection of Animal Pathogenic Micro-organisms, Brno, Czechoslovakia
Centraalbureau voor Schimmelcultures, Baarn, The Netherlands
Czechoslovak Collection of Entomogenous Bacteria(Institute of Entomology), Prague, Czechoslovakia
Czechoslovak Collection of Microorganisms, J.E. Purkyne University, Brno, Czechoslovakia
Centre de Collection de Type Microbienne, Lille, France
Culture Collection of the University of Göteborg,Göteborg, Sweden
California Department of Animal Investigation, California, USA
Centers for Disease Control (formerly Communicable Disease Center), Atlanta, Georgia , USA
Designation supplied by the PHLS at Cambridge
Coleccion Espanola de Cultivos Tipo, Valencia, Spain
Maintenance or cultivation of cells in vitro in which the cells are no longer organised into tissues. Origin tissue is disassociated by cell migration or mechanical or enzymic means.
The series of activities that each cell goes through. There are 5 recognised phases of the cell cycle: G0 - rest phase, G1 - 1st gap phase where cells prepare to synthesise DNA and undego mass synthesis, S - cells synthesise DNA and double 2n to 4n, G2 - 2nd gap phase where the cells prepare to divide and M - mitosis.
The interval between consecutive divisions of a cell.
The fusion of two or more dissimilar cells leading to the formation of a synkaryon.
A cell line arises from a primary culture of the first successful sub-culture. The term cell line implies that cultures from it consist of lineages of cells originally present in the primary culture. The terms finite or continuous are used as prefixes if the status of the culture is known. If not, the term line will suffice. The term 'continuous line' replaces the term 'established line'. In any published description of a culture, one must make every attempt to publish the characterization or history of the culture. If such has already been published, a reference to the original publication must be made. In obtaining a culture from another laboratory, the proper designation of the culture, as originally named and described, must be maintained and any deviations in cultivation from the original must be reported in any publication.
A description of the stage of growth that a cell population is in. There are 4 recognised phases: Lag Phase - where there is no net increase in cell number as the cells adapt to their environment, Log/Exponential Phase - where the population increases exponentially, Plateau - no net increase in cell numbers as the limits of space, nutrients and other factors are reached and Death/Decline Phase - where there is a net decrease in the population as the cells begin to die. Cell phases are pictorially represented as a growth curve.
A cell strain is derived either from a primary culture or a cell line by the selection or cloning of cells having specific properties or markers.
Florida State Health Department, Florida, USA
A nutritive solution for culturing cells in which each component is specifiable and, ideally, is of known chemical structure.
Collection de l'Institut Pasteur (see also CNCM), Paris, France
Collection de l'Institut Pasteur, Lyon, France
NCTC (Computer Laboratory, e.g. CL34/78), strain originally received for identification
The extent to which one clone is similar to another.
Wellcome Collection of Bacteria, Burroughs Wellcome Research Laboratories, Beckenham, Kent , UK
Collection Nationale de Cultures de Micro-organismes (formerly CIP), Institut Pasteur, Paris, France
Salmonella Reference Laboratory (Laboratory of Enteric Pathogens), HPA Centre for Infections, London, UK
The percentage of cells plated (seeded, inoculated) that form a colony. Also known as plating efficiency.
Medium containing growth factors secreted by other cells.
The percentage to which adherent cells cover the substrate (eg Flask). Note that cells should regularly be subcultured at around 60-70% confluency but please refer to the cell line data sheet or catalogue information as some cell lines do not reach this level of confluency.
The property of a cell to cease division when in contact with neighbouring cells or when growing in restricted space
A culture that is apparently capable of an unlimited number of population doublings; often referred to as an immortal cell culture. Such cells may or may not express the characteristics of in vitro neoplastic or malignant transformation. (See also 'immortalisation' )
Cytopathic effect caused by viral infection of cell lines, causing the morphology to change.
Central Public Health Laboratory, now HPA Centre for Infections, London, UK
Clinical Research Centre, Harrow, UK
When one cell culture has been introduced to another giving rise to a mixed cell population. If once cell type grows more vigorously than the other then that cell type will prevail.
Ultra-low temperature storage of cells, tissues, embryos or seeds. This storage is usually carried out in the vapour or liquid phase of nitrogen.
Commonwealth Scientific and Industrial Research Organization, Australia
Collection de l'Unite d'Ecotoxicologie Microbienne,Villeneuve d'Ascq, France
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