Figure 1: Number of publications citing the term 'iPSC'. Data sourced from Google Scholar
Induced pluripotent stem cells (iPSCs) are increasingly being used in research. The number of publications citing the use of iPSCs is increasing every year as seen in Figure 1 above.
To assist scientists in their research, ECACC provide quality-controlled and disease-relevant iPSC lines for academic, not-for-profit and commercial laboratories worldwide. The two iPSC collections distributed by ECACC are the HipSci collection and the EBiSC collection. These resources provide researchers with a choice of over 1,500 iPSC lines derived from blood and tissue samples, from male and female subjects of various ages, and represent a wide variety of rare and more prevalent diseases.
Below is a selection of recent publications that have cited the use of iPSC lines avaiable from the HipSci and EBiSC collections via the ECACC catalogue.
|2019||The role of Nav1.7 in human nociceptors: insights from human induced pluripotent stem cell-derived sensory neurons of erythromelalgia patients.|
|2019||Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes.|
|2019||The Academic Pill: How Academia Contributes to Curing Diseases.|
|2019||Zooming in on Cryopreservation of hiPSCs and Neural Derivatives: A Dual-Center Study Using Adherent Vitrification.|
|2019||Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors.|
|2019||Combined single-cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity.|
|2019||CRISPR/Cas9-mediated one step bi-allelic change of genomic DNA in iPSCs and human RPE cells in vitro with dual antibiotic selection.|
|2019||Genetic effects on promoter usage are highly context-specific and contribute to complex traits.|
|2019||Induction of Neural Crest Stem Cells From Bardet-Biedl Syndrome Patient Derived hiPSCs.|
|2018||Gene expression variability across cells and species shapes innate immunity.|
|2018||BioSamples database: an updated sample metadata hub.|
|2018||RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation.|
|2018||The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans.|
|2018||The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients.|
Prepared by Sharon Bahia.
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