As a call for action to combat the use of misidentified and cross-contaminated cell lines, Dr Roland Nardone supported by a panel of cell culture experts, including ECACC, submitted an open letter to Secretary Michael Leavitt of the U.S. Department of Health and Human Services. The letter highlights the grave consequences of the continued failure of many users of cell cultures to take appropriate precautions to verify cell line identity and recommends approaches to end this failure. The recommendations include establishing cell culture practice compliance policies and education initiatives across the research community enforced by grant funding agencies and journals.
Excerpt from the letter, measures proposed to enforce compliance:
'We advocate that all researchers using cell cultures incorporate a specific cell line authentication protocol into their experimental framework and the first approach virtually ensures compliance:
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