Culture Collections

NCTC in research: Detecting Salmonella in animal feed

Salmonella infection is a major global cause of foodborne disease and is frequently transmitted as a result of the consumption of contaminated foods of animal origin; contamination in animal feed is known to be a contributing factor. Rapid methods for identifying Salmonella-free samples are being developed which have the potential to reduce the turnaround time for negative results from three to two days.

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CHO Cell Lines Expressing Fcγ Receptors

New CHO cell line variants, expressing different classes of Fc gamma receptors (FcγRs) have been deposited exclusively into the ECACC General Collection by Cambridge Enterprise Limited, UK. The variant lines were developed in the laboratory of Dr. Mike Clark at Cambridge University and include five cell lines that express three different human FcγRs including allotypes of FcγRIIa and FcγRIIIa.

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Reproducibility in pre-clinical life science research

Reproducibility forms the foundation of meaningful scientific research and is an issue which is causing increasing concern. The causes are complex and include lack of validation of key biological reagents and reference material (including cell lines), poor study design, inadequate data analysis and reporting and a lack of robust laboratory protocols. This means that the solutions will be complex and will require the concerted effort of all stakeholders involved in the pre-clinical science fields including scientists, journals, funding bodies and even mainstream media.

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Why Choose Us?

Public Health England (PHE) is the custodian of four unique collections that consist of expertly preserved, authenticated cell lines and microbial strains of known provenance for use in medical science and laboratory healthcare.

All the collections are developed, managed and maintained by highly trained, dedicated staff who work in accordance with internationally recognised quality standards including certification to ISO 9001:2008.

Cultures from the collections are used by scientists who need to reassure themselves and others that the materials they are using are authentic, so the conclusions to their studies are valid and relevant. This is particularly important where research may lead to peer-reviewed publications, for example, in drug discovery and vaccine efficacy studies. Authenticated reference strains are also of paramount importance for clinical diagnostic testing, food, water and environmental microbiology testing and validation studies.

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ECACC ICON Small size

Cell lines

The European Collection of Authenticated Cell Cultures (ECACC) maintains and supplies over 40,000 cell lines and their derivatives such as DNA, RNA and cDNA.



NCTC ICON small size


The National Collection of Type Cultures (NCTC) maintains and supplies over 5,000 bacteria and mycoplasma strains.



NCPV ICON small size


The National Collection of Pathogenic Viruses (NCPV) maintains and supplies over 700 viruses and viral nucleic acid.



NCPF ICON small size


The National Collection of Pathogenic Fungi (NCPF) maintains and supplies over 4000 fungal strains.


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