Culture Collections

Hazard Group 3 bacteria in the NCTC collection

In the UK, biological agents are classified into four Hazard Groups (HG1-4). Similar categorisations of biological agents are also seen in other parts of the world. The majority of bacteria within the NCTC collection fall within the HG2 category; however, the collection also holds over 500 strains of HG3 bacteria.

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10 Years of Human iPS Cells

In 2006 Professor Shinya Yamanaka first presented the work of his team showing that just four transcription factors were required to transform a skin cell into a pluripotent stem cell. This technology is now called reprogramming and the cells generated from its use are termed induced pluripotent stem (iPS) cells.

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Exophiala campbellii: a new fungal species

The Mycology Reference Laboratory recently undertook a study of Exophiala species contained within the NCPF collection to see they could distinguish between them using MALDI-ToF technology. Read Dr Elizabeth Johnson’s account of how this investigation led to the identification of a new species.

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Why Choose Us?

Public Health England (PHE) is the custodian of four unique collections that consist of expertly preserved, authenticated cell lines and microbial strains of known provenance for use in medical science and laboratory healthcare.

All the collections are developed, managed and maintained by highly trained, dedicated staff who work in accordance with internationally recognised quality standards including certification to ISO 9001:2008.

Cultures from the collections are used by scientists who need to reassure themselves and others that the materials they are using are authentic, so the conclusions to their studies are valid and relevant. This is particularly important where research may lead to peer-reviewed publications, for example, in drug discovery and vaccine efficacy studies. Authenticated reference strains are also of paramount importance for clinical diagnostic testing, food, water and environmental microbiology testing and validation studies.

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ECACC

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Cell lines

The European Collection of Authenticated Cell Cultures (ECACC) maintains and supplies over 40,000 cell lines and their derivatives such as DNA, RNA and cDNA.

 

NCTC

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Bacteria

The National Collection of Type Cultures (NCTC) maintains and supplies over 5,000 bacteria and mycoplasma strains.

 

NCPV

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Viruses

The National Collection of Pathogenic Viruses (NCPV) maintains and supplies over 700 viruses and viral nucleic acid.

 

NCPF

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Fungi

The National Collection of Pathogenic Fungi (NCPF) maintains and supplies over 4000 fungal strains.

 

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