Culture Collections

ECACC in research: CHO-K1 cells used in targeted nucleotide editing study

Prokaryotes such as bacteria display adaptive immunity through a mechanism called CRISPR/Cas. An adapted CRISPR/Cas system has recently been adopted by scientists as a gene editing tool for eukaryoke cells. In a recent study, Nishida and colleagues studied the use a hybrid vertebrate-prokaryote system to investigate its use in single nucleotide editing.

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NCPF in research: Pathogenicity of C.auris as an emerging pathogen

Candida auris is an emerging fungal pathogen first isolated from the ear of a patient from Japan in 2009. It has subsequently been isolated from several sites of infection including the bloodstream and from skin wounds world-wide, and is of concern due to its multi-drug resistant nature and high mortality rate. In addition, C. auris has been shown to have the ability to readily transfer between hospital patients setting it apart from the majority of Candida species.

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Serum-free products survey

Serum is an essential reagent for cell culture and is included in cell culture media as a source of growth and adhesion factors, hormones, lipids and minerals. One disadvantage to serum use is the possible contamination with viruses. Would you like your NCPV viruses to be grown in serum free media? Complete our customer consultation survey online.

 

 

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Why Choose Us?

Public Health England (PHE) is the custodian of four unique collections that consist of expertly preserved, authenticated cell lines and microbial strains of known provenance for use in medical science and laboratory healthcare.

All the collections are developed, managed and maintained by highly trained, dedicated staff who work in accordance with internationally recognised quality standards including certification to ISO 9001:2008.

Cultures from the collections are used by scientists who need to reassure themselves and others that the materials they are using are authentic, so the conclusions to their studies are valid and relevant. This is particularly important where research may lead to peer-reviewed publications, for example, in drug discovery and vaccine efficacy studies. Authenticated reference strains are also of paramount importance for clinical diagnostic testing, food, water and environmental microbiology testing and validation studies.

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ECACC

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Cell lines

The European Collection of Authenticated Cell Cultures (ECACC) maintains and supplies over 40,000 cell lines and their derivatives such as DNA, RNA and cDNA.

 

NCTC

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Bacteria

The National Collection of Type Cultures (NCTC) maintains and supplies over 5000 bacteria and mycoplasma strains.

 

NCPV

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Viruses

The National Collection of Pathogenic Viruses (NCPV) maintains and supplies over 700 viruses and viral nucleic acid.

 

NCPF

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Fungi

The National Collection of Pathogenic Fungi (NCPF) maintains and supplies over 4000 fungal strains.

 

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