Culture Collections

Depositing a cell line with ECACC

Depositing a cell line with ECACC: the strengths of quality control, storage and distribution Cell lines are increasingly critical tools for life science research and as concerns over scientific reproducibility grow, it is essential that they are of known origin, and they are valid in terms of identity, freedom from microbial contamination and function. ECACC maintains secure master and working banks of cryopreserved stocks of the cell lines in its collection.

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NCTC Mycobacteria strains in research

Many researchers use NCTC strains during the development, evaluation and validation of laboratory methods.  A team at Queen’s University, Belfast, UK, used NCTC Mycobacteria strains to evaluate an assay for the rapid detection of Mycobacterium avium subsp. paratuberculosis (MAP) in milk. MAP causes Johne’s disease (JD), a chronic enteric wasting disease that affects domestic ruminants. 

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Global supply of healthcare products: the M. chimaera challenge

NCTC is working to provide authenticated reference strains of Mycobacterium chimaera. The type strain is now available as NCTC 13781. Until fairly recently M.chimaera was a low profile microorganism in the sphere of human infection. However, this changed in 2014 when six cases of severe infection were reported in cardiac surgery patients in Zurich.

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Why Choose Us?

Public Health England (PHE) is the custodian of four unique collections that consist of expertly preserved, authenticated cell lines and microbial strains of known provenance for use in medical science and laboratory healthcare.

All the collections are developed, managed and maintained by highly trained, dedicated staff who work in accordance with internationally recognised quality standards including certification to ISO 9001:2008.

Cultures from the collections are used by scientists who need to reassure themselves and others that the materials they are using are authentic, so the conclusions to their studies are valid and relevant. This is particularly important where research may lead to peer-reviewed publications, for example, in drug discovery and vaccine efficacy studies. Authenticated reference strains are also of paramount importance for clinical diagnostic testing, food, water and environmental microbiology testing and validation studies.

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ECACC

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Cell lines

The European Collection of Authenticated Cell Cultures (ECACC) maintains and supplies over 40,000 cell lines and their derivatives such as DNA, RNA and cDNA.

 

NCTC

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Bacteria

The National Collection of Type Cultures (NCTC) maintains and supplies over 5,000 bacteria and mycoplasma strains.

 

NCPV

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Viruses

The National Collection of Pathogenic Viruses (NCPV) maintains and supplies over 700 viruses and viral nucleic acid.

 

NCPF

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Fungi

The National Collection of Pathogenic Fungi (NCPF) maintains and supplies over 4000 fungal strains.

 

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