Culture Collections

General Cell Collection Detail

Cell Line Authentication & Quality Control Information

General Cell Collection: COV434

Catalogue No.: 07071909
Cell Line Name: COV434
Keywords: Human ovarian granulosa tumour
Cell Line Description: Human ovarian granulosa tumour cell line established from a solid primary tumour.
Species: Human
Tissue: Ovary
Morphology: Polygonal & fusiform
Growth Mode: Adherent
DNA Profile: STR-PCR Data:

Amelogenin: X
CSF1PO: 10,11
D13S317: 8,12
D16S539: 9,12
D5S818: 10,11
D7S820: 8
THO1: 9.3
TPOX: 9,11
vWA: 16,18

Subculture Routine: Split confluent cultures 1:2 to 1:5 i.e. seeding at 2-4x10,000 cells/cm² using trypsin/EDTA; 5% CO2; 37°C.
Culture Medium: DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS)
Karyotype: Modal chromosome no. 47 (46 - 47)
Depositor: Dr C E van der Minne, S H van der Burg & P I Schrier, Department of Clinical Oncology, Leiden University Medical Centre, Albinusdreef 2 K-I-P, 2333 ZA Leiden, Netherlands.
Originator: Yes
Country: Netherlands
References: van den Berg-Bakker CA, Hagemeijer A, Franken-Postma EM, Smit VT, Kuppen PJ, van Ravenswaay Claasen HH, Cornelisse CJ, Schrier PI 1993 Establishment and characterization of 7 ovarian carcinoma cell lines and one granulosa tumor cell line: growth features and cytogenetics. Int J Cancer. 53(4):613-20 PMID: 8436435.
Additional Bibliography: Barretina J, et al., 2012 The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature. 483(7391):603-7. PMID: 22460905.
Patents: None Specified By Depositor
Research Council Deposit: No
Release Conditions: No

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The Culture Collections represent deposits of cultures from world-wide sources. While every effort is made to ensure details distributed by Culture Collections are accurate, Culture Collections cannot be held responsible for any inaccuracies in the data supplied. References where quoted are mainly attributed to the establishment of the cell culture and not for any specific property of the cell line, therefore further references should be obtained regarding cell culture characteristics. Passage numbers where given act only as a guide and Culture Collections does not guarantee the passage number stated will be the passage number received by the customer.

Cultures supplied by Culture Collections are for research purposes only. Enquiries regarding the commercial use of a cell line are referred to the depositor of the cell line. Some cell lines have additional special release conditions such as the requirement for a material transfer agreement to be completed by the potential recipient prior to the supply of the cell line. Please view the Terms & Conditions of Supply for more information.

Available Formats

DNA-5µg (100ng/µl)
RNA-5µg (100ng/µl)

  • Frozen
  • Growing
  • DNA-5µg (100ng/µl)
  • RNA-5µg (100ng/µl)
  • cDNA-20µl

This product is only available through your local distributor.

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